Transactions of the National Academy of Science and Technology
Pimentel, Stephanie S.
Roldan, Eufemio Jesus R., Golez, Phillip Sebastian Serafin J.
Aeromonas hydrophila is an opportunistic bacterial pathogen of a number of aquatic animals that causes hemorrhagic septicemias, erythrodermatitis, fin and tail rot in fish. The pathogen affects Oreochromis niloticus (Nile tilapia), an economically important cultured fish in the Philippines. In this study, the protective effects of formalin- or autoclave-killed A. hydrophila or bacterin where injected via intraperitoneal on O. niloticus then challenged with live A. hydrophila. Data on mortality rates, serum lysozyme levels and histopathology of immune related organs, head kidney and spleen, generated responses in the challenged fish. Though fish were not entirely protected from the live form, autoclaved-killed bacteria showed stronger immune responses compared to formalin-killed bacteria. (Author's abstract)